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Hoehe M, 1988. Influence of the menstrual cycle on neuroendocrine and behavioral responses to an opiate agonist in humans: preliminary results. Psychoneuroendocrinology

If coadministration of CYP3A4 inhibitors with fentanyl is essential, keep track of patients for respiratory depression and sedation at Regular intervals and consider fentanyl dose changes right up until stable drug effects are reached.

drospirenone will increase the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.

If coadministration of CYP3A4 inhibitors with fentanyl is important, monitor patients for respiratory depression and sedation at Regular intervals and consider fentanyl dose adjustments until stable drug effects are accomplished.

carbamazepine will lessen the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers could lead to your decrease in fentanyl plasma concentrations, deficiency of efficacy or, probably, enhancement of a withdrawal syndrome inside a affected individual who has developed Bodily dependence to fentanyl.

lenacapavir will enhance the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

If coadministration of CYP3A4 inhibitors with fentanyl is important, keep track of patients for respiratory depression and sedation at Regular intervals and consider fentanyl dose changes until finally stable drug effects are attained.

Monoamine oxidase inhibitors (MAOIs) might potentiate effects of opioid, opioid’s active metabolite, which include respiratory depression, coma, and confusion; therapy should not be administered within fourteen days of initiating or halting MAOIs

Observe Intently (1)pirtobrutinib will increase the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

efavirenz will lessen the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to some decrease in fentanyl plasma concentrations, lack of efficacy or, probably, improvement of a withdrawal syndrome in fentanyl what it do the affected individual who may have made Bodily dependence to fentanyl.

If you need to visit a&E, will not travel yourself. Get some other person to push you or demand an ambulance.

If coadministration of CYP3A4 inhibitors with fentanyl is essential, observe patients for respiratory depression and sedation at frequent intervals and consider fentanyl dose adjustments until stable drug effects are reached.

anastrozole will boost the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.

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